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Fig. 7 RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC <t>iota</t> inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001
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Fig. 7 RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC <t>iota</t> inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001
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prkci inhibitor 1  (MedChemExpress)
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Fig. 7 RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC <t>iota</t> inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001
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https://www.bioz.com/product/pkc-iota+inhibitor+1/PKC-iota+inhibitor+1/pm35869269-229-0-6
Average 91 stars, based on 1 article reviews
prkci inhibitor 1 - by Bioz Stars, 2026-10
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Fig. 7 RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC iota inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001

Journal: Molecular medicine (Cambridge, Mass.)

Article Title: Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation.

doi: 10.1186/s10020-023-00648-z

Figure Lengend Snippet: Fig. 7 RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC iota inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001

Article Snippet: PKC-iota inhibitor 1 (Topscience, Shanghai, China) was added in a concentration of 10 μM for Panc1 and 100 μM for Mia paca2.

Techniques: Expressing, Immunofluorescence, Inhibition

Fig. 8 PKC iota inhibition affected the expression of RIPK2 and the phosphorylation of NF-κB, JNK and ERK. *p < 0.05, **p < 0.01, ***p < 0.001, ns not significant

Journal: Molecular medicine (Cambridge, Mass.)

Article Title: Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation.

doi: 10.1186/s10020-023-00648-z

Figure Lengend Snippet: Fig. 8 PKC iota inhibition affected the expression of RIPK2 and the phosphorylation of NF-κB, JNK and ERK. *p < 0.05, **p < 0.01, ***p < 0.001, ns not significant

Article Snippet: PKC-iota inhibitor 1 (Topscience, Shanghai, China) was added in a concentration of 10 μM for Panc1 and 100 μM for Mia paca2.

Techniques: Inhibition, Expressing, Phospho-proteomics